Education
M.Tech.
Chemical Engineering, Indian Institute of Technology Delhi (2017)
B.Tech.
Chemical Engineering, Indian Institute of Technology Delhi (2017)
Publications
Saha, B., Mathur, T., Tronolone, J. J., Chokshi, M., Lokhande, G. K., Selahi, A., Gaharwar, A. K., Afshar-Khargan, V., Sood, A. K., Bao, G., & Jain, A. Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer. Sci. Adv. 2021;7(30):eabg5283.
doi: 10.1126/sciadv.abg5283.
Mathur, T., Flanagan, J. M., & Jain, A. Tripartite collaboration of blood-derived endothelial cells, next generation RNA sequencing and bioengineered vessel-chip may distinguish vasculopathy and thrombosis amongst sickle cell disease patients. Bioeng. Transl. Med. 2021;e10211.
doi: 10.1002/btm2.10211.
Saha, B., Mathur, T., Handley, K. F., Hu, W., Afshar-Kharghan, V., Sood, A. K., & Jain, A. OvCa-Chip microsystem recreates vascular endothelium–mediated platelet extravasation in ovarian cancer. Blood Adv. 2020 July 27;4 (14): 3329–3342.
doi: 10.1182/bloodadvances.2020001632.
Luna, D. J., Pandian, N. K. R., Mathur, T., Gadangi, P., Kostousov, V. V., Hui, S.-K. R., Teruya, J., & Jain, A. Tortuosity-powered microfluidic device for assessment of thrombosis and antithrombotic therapy in whole blood. Sci Rep. 2020 Apr 1;10:5742.
doi: 10.1038/s41598-020-62768-4.
Mathur, T., Singh, K. A., Pandian, N. K. R., Tsai, S. H., Hein, T. W., Gaharwar, A. K., Flanagan, J. M., & Jain, A. Organ-on-Chips made of Blood: Endothelial Progenitor Cells from Blood reconstitute Vascular Thromboinflammation in Vessel-Chips. Lab Chip. 2019 Jul 23;19(15):2500-2511.
doi: 10.1039/c9lc00469f.
Book Chapters
Jain, A., Mathur, T., Pandian, N. K. R., & Selahi, A . Organ-on-a-chip and 3D printing as preclinical models for medical research and practice. In Precision Medicine for Investigators, Practitioners and Providers (pp. 83-95). Academic Press.
doi: 10.1016/C2018-0-03029-7
Oral Presentations
Mathur, T., Singh, K. A., Tsai, S. H., Hein, T. W., Gaharwar, A. K., Flanagan, J. M., & Jain, A.
Organ-on-Chips made of Blood: Endothelial Progenitor Cells from Blood reconstitute Vascular Thromboinflammation of Diabetic Patients in Vessel-Chips. Biomedical Engineering Society Annual Meeting, Philadelphia, PA, USA. 2019.
Mathur, T., Hein, T. W., Flanagan, J. M., & Jain, A. Blood Endothelial Progenitor Cell-on-a-chip: A Disease and Patient-specific Cell Source for In Vitro Vascular Tissue Engineered Platforms. XXVII Congress and 65th Annual Scientific and Standardization Committee (SSC) Meeting of International Society on Thrombosis and Hemostasis, Melbourne, Australia. 2019.
Mathur, T., Hein, T. W., Flanagan, J. M., & Jain, A. Blood Progenitor Endothelial Cells-on-a-chip: A Disease and Patient-specific Cell Source for Vascular Medical Devices. American Heart Association Vascular Discovery Meeting, Boston, MA, USA. 2019.
Mathur, T., Flanagan, J. M., & Jain, A. A Disease and Patient-Specific Artery-on-a-Chip System to Model Thromboinflammation in Sickle Cell Disease. Biomedical Engineering Society Annual Meeting, Atlanta, GA, USA. 2018.
Poster Presentations
Mathur, T., Singh, K. A., Tsai, S. H., Hein, T. W., Gaharwar, A. K., Flanagan, J. M., & Jain, A.
Organ-on-Chips made of Blood: Endothelial Progenitor Cells from Blood reconstitute Vascular Thromboinflammation of Diabetic Patients in Vessel-Chips. Gulf Coast Vascular Research Consortium, Houston Methodist Research Institute, Houston, TX, USA. 2019.
Mathur, T., Flanagan, J. M., & Jain, A. A disease and patient-specific artery-on-a-chip system to model thromboinflammation in sickle cell disease. Microscopy and Imaging Center Open House, Texas A&M University, College Station, TX, USA. October 5, 2018
Mathur, T., Flanagan, J. M., & Jain, A. A patient-derived artery-on-a-chip model of thromboinflammation in sickle cell disease. Gulf Coast Vascular Research Consortium, College Station, TX, USA. 2018.